AZ304
Product Specifications
CAS Number
942507-42-8
Target
Raf
Applications
MAPK
Smiles
CC1=C (C=C (C=C1) NC (=O) C2=CC (=CC=C2) C (C) (C) C#N) NC3=NC=NC4=C3C=CC (=C4) OC
Molecular Formula
C27H25N5O2
Additionnal Information
AZ304 is a synthetic inhibitor designed to interact with the ATP-binding site of wild type and V600E mutant BRAF with IC50 values of 79 nM and 38 nM, respectively. It also inhibits CRAF, p38 and CSF1R at sub 100 nM potencies.
Storage Conditions
3 years -20°C powder
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