Alofanib (RPT835)
Product Specifications
CAS Number
1612888-66-0
Target
FGFR
Applications
Protein Tyrosine Kinase
Smiles
CC1=CC (=C (C=C1C2=CN=CC=C2) NS (=O) (=O) C3=CC=CC (=C3) C (=O) O) [N+] (=O) [O-]
Molecular Formula
C19H15N3O6S
Additionnal Information
Alofanib (RPT835) is a novel selective allosteric inhibitor of FGFR2 and has a dramatic inhibitory effect with IC50 <10 nM on FGF2-induced phoshphorylation of FRS2a in KATO III cells. It has no direct effect on FGF2-dependent FGFR1 and FGFR3 phosphorylation levels in either cell lines and no effects on FGF2-FGFR2 binding.
Storage Conditions
3 years -20°C powder
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS1141924-01 0.02 mg (E-Coli)
Recombinant Streptococcus pneumoniae UPF0246 protein SP70585_1589 (SP70585_1589)
Sign In for Pricing
View Details MBS1141924-02 0.1 mg (E-Coli)
Recombinant Streptococcus pneumoniae UPF0246 protein SP70585_1589 (SP70585_1589)
Sign In for Pricing
View Details MBS1141924-03 0.02 mg (Yeast)
Recombinant Streptococcus pneumoniae UPF0246 protein SP70585_1589 (SP70585_1589)
Sign In for Pricing
View Details