What is the catalog number for Alofanib (RPT835)?

The catalog number for Alofanib (RPT835) is C13642-25mg.

What sizes are available for Alofanib (RPT835)?

Alofanib (RPT835) is available in the following size(s): 25 mg.

Is Alofanib (RPT835) in stock?

Alofanib (RPT835) is currently made to order / not held in immediate stock. Contact us for lead time.

Alofanib (RPT835)

Product Specifications

CAS Number

1612888-66-0

Target

FGFR

Applications

Protein Tyrosine Kinase

Smiles

CC1=CC (=C (C=C1C2=CN=CC=C2) NS (=O) (=O) C3=CC=CC (=C3) C (=O) O) [N+] (=O) [O-]

Molecular Formula

C19H15N3O6S

Additionnal Information

Alofanib (RPT835) is a novel selective allosteric inhibitor of FGFR2 and has a dramatic inhibitory effect with IC50 <10 nM on FGF2-induced phoshphorylation of FRS2a in KATO III cells. It has no direct effect on FGF2-dependent FGFR1 and FGFR3 phosphorylation levels in either cell lines and no effects on FGF2-FGFR2 binding.