Tropifexor (LJN452)
Product Specifications
CAS Number
1383816-29-2
Target
FXR
Applications
Metabolism
Smiles
C1CC1C2=C (C (=NO2) C3=CC=CC=C3OC (F) (F) F) COC4CC5CCC (C4) N5C6=NC7=C (C=C (C=C7S6) C (=O) O) F
Molecular Formula
C29H25F4N3O5S
Additionnal Information
Tropifexor (LJN452) is a novel and highly potent agonist of FXR with EC50 of 0.2 nM in HTRF assay. It shows no significant off-target activity against a broad panel of enzyme, ion channel, nuclear receptor, and GPCR (>10000-fold selectivity for FXR) .
Storage Conditions
3 years -20°C powder
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS1062494-01 0.02 mg (E-Coli)
Recombinant Yersinia enterocolitica Urease accessory protein UreD (ureD)
Sign In for Pricing
View Details MBS1062494-02 0.02 mg (Yeast)
Recombinant Yersinia enterocolitica Urease accessory protein UreD (ureD)
Sign In for Pricing
View Details MBS1062494-03 0.1 mg (E-Coli)
Recombinant Yersinia enterocolitica Urease accessory protein UreD (ureD)
Sign In for Pricing
View Details MBS1062494-04 0.1 mg (Yeast)
Recombinant Yersinia enterocolitica Urease accessory protein UreD (ureD)
Sign In for Pricing
View Details MBS1062494-05 0.02 mg (Baculovirus)
Recombinant Yersinia enterocolitica Urease accessory protein UreD (ureD)
Sign In for Pricing
View Details