PDGFR inhibitor 1
Product Specifications
CAS Number
1225278-16-9
Target
C-Kit
Applications
Protein Tyrosine Kinase
Smiles
CN1C=C (C=N1) C2=NC=CC (=C2) OC3=C (C=C (C (=C3) F) NC (=O) C4 (CC4) C (=O) NC5=CC=CC=C5) F
Molecular Formula
C26H21F2N5O3
Additionnal Information
PDGFR inhibitor 1 is an orally bioavailable switch pocket control inhibitor of wild-type and mutated forms of Kit (c-Kit) and PDGFR with potential antineoplastic activity. It also inhibits several other kinases, including VEGFR2, TIE2, PDGFR-beta and CSF1R, thereby further inhibiting tumor cell growth.
Storage Conditions
3 years -20°C powder
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