Nemtabrutinib (ARQ 531)
Product Specifications
CAS Number
2095393-15-8
Synonyms
MK-1026
Target
BTK
Applications
Protein Tyrosine Kinase
Smiles
C1CC (OCC1NC2=NC=NC3=C2C (=CN3) C (=O) C4=C (C=C (C=C4) OC5=CC=CC=C5) Cl) CO
Molecular Formula
C25H23ClN4O4
Additionnal Information
Nemtabrutinib (ARQ 531, MK-1026) is an ATP-competitive tyrosine kinase inhibitor designed to target BTK with an IC50 of 0.85 nM. It also has a distinct kinase selectivity profile with strong inhibitory activity against several key oncogenic drivers from TEC, Trk and Src family kinases.
Storage Conditions
3 years -20°C powder
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