Selective JAK3 inhibitor 1
Product Specifications
CAS Number
1443235-95-7
Target
JAK
Applications
Angiogenesis
Smiles
CCOC (=O) C1=CNC2=NC=NC (=C12) C3=CC (=CC=C3) NC (=O) C (=C) C
Molecular Formula
C19H18N4O3
Additionnal Information
Selective JAK3 inhibitor 1 is an irreversible JAK3 inhibitor with Ki values of 0.07 nM, 320 nM, 740 nM for JAK3, JAK1 and JAK2 respectively. It is also selective over the other kinases possessing a cysteine in the same region as JAK3, such as BMX, EGFR, ITK, and BTK.
Storage Conditions
3 years -20°C powder
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M8-L18SP-50H 20 Mounts
20 each of 50x500 µm aperture Horizontal MicroLoops E; mounted on 18 mm rods
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