AMG 487
Product Specifications
CAS Number
473719-41-4
Target
CXCR
Applications
GPCR & G Protein
Smiles
CCOC1=CC=C (C=C1) N2C (=O) C3=CC=CN=C3N=C2C (C) N (CC4=CC=CN=C4) C (=O) CC5=CC=C (OC (F) (F) F) C=C5
Molecular Formula
C32H28F3N5O4
Additionnal Information
AMG 487 is an orally active and selective CXC chemokine receptor 3 (CXCR3) antagonist that inhibits the binding of IP-10 (CXCL10) and ITAC (CXCL11) to CXCR3 with IC50 of 8.0 nM and 8.2 nM, respectively.
Storage Conditions
3 years -20°C powder
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![2-[ (5-Amino-1H-1,2,4-triazol-3-yl) sulfanyl]ethan-1-ol](https://cdn.genprice.uk/genprice/uk/genprice3.webp)
RMB86793-01 50 mg
2-[ (5-Amino-1H-1,2,4-triazol-3-yl) sulfanyl]ethan-1-ol
Sign In for Pricing
View Details RMB86793-02 0.5 g
2-[ (5-Amino-1H-1,2,4-triazol-3-yl) sulfanyl]ethan-1-ol
Sign In for Pricing
View Details 
RAA23189-01 100 mg
2-Chloro-N- (2-cyanoethyl) -N- (2-methoxyphenyl) acetamide
Sign In for Pricing
View Details RAA23189-02 1 g
2-Chloro-N- (2-cyanoethyl) -N- (2-methoxyphenyl) acetamide
Sign In for Pricing
View Details MBS1123672-01 0.02 mg (E-Coli)
Recombinant Escherichia coli O157:H7 Secreted effector protein EspF (U)
Sign In for Pricing
View Details