What is the catalog number for Tolinapant (ASTX660)?

The catalog number for Tolinapant (ASTX660) is C13586-1mg.

What sizes are available for Tolinapant (ASTX660)?

Tolinapant (ASTX660) is available in the following size(s): 1 mg.

Is Tolinapant (ASTX660) in stock?

Tolinapant (ASTX660) is currently made to order / not held in immediate stock. Contact us for lead time.

Tolinapant (ASTX660)

Product Specifications

CAS Number

1799328-86-1

Target

IAP

Applications

Apoptosis

Smiles

CC1CN (C (CN1) CN2CCOCC2C) CC (=O) N3CC (C4=C3C=C (C (=N4) CO) CC5=CC=C (C=C5) F) (C) C

Molecular Formula

C30H42FN5O3

Additionnal Information

Tolinapant (ASTX660) is a potent, non-peptidomimetic antagonist of cIAP1/2 and XIAP that inhibits the interactions between a SMAC-derived peptide and the BIR3 domains of XIAP (BIR3-XIAP) and cIAP1 (BIR3-cIAP1) with IC50 values less than 40 and 12 nmol/L, respectively.