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Cu-CPT22

Product Specifications

CAS Number

1416324-85-0

Target

TLR

Applications

Immunology & Inflammation

Smiles

CCCCCCOC (=O) C1=CC2=C (C (=C (O) C (=C2) OC) O) C (=O) C (=C1) O

Molecular Formula

C19H22O7

Additionnal Information

CU-CPT22 shows dose-dependent inhibitory effects blocking Pam3CSK4-induced TLR1/2 activation with an IC50 of 0.58 ± 0.09 μM while no significant inhibition to TLR2/6. It demonstrates minimal non-specific inhibition against a panel of 10 representative kinases (PDGFRB, MET, DDR2, SRC, MAPK1, PAK1, AKT1, PKC-γ, CAMK1, and PLK4) .

Storage Conditions

2 years -80 in solvent

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