Glumetinib
Product Specifications
CAS Number
1642581-63-2
Synonyms
SCC244
Target
C-Met
Applications
Protein Tyrosine Kinase
Smiles
CN1C=C (C=N1) C2=CN3C (=NC=C3S (=O) (=O) N4C5=C (C=N4) N=CC (=C5) C6=CN (N=C6) C) C=C2
Molecular Formula
C21H17N9O2S
Additionnal Information
Glumetinib is a potent and highly selective c-Met inhibitor with an IC50 of 0.42 ± 0.02 nmol/L. Glumetinib has greater than 2,400-fold selectivity for c-Met over those 312 kinases evaluated, including the c-Met family member RON and highly homologous kinases Axl, Mer, and TyrO3.
Storage Conditions
3 years -20°C powder
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