Tenalisib
Product Specifications
CAS Number
1639417-53-0
Synonyms
RP6530
Target
PI3K
Applications
PI3K/Akt/mTOR
Smiles
CCC (C1=C (C (=O) C2=CC=CC=C2O1) C3=CC (=CC=C3) F) NC4=NC=NC5=C4NC=N5
Molecular Formula
C23H18FN5O2
Additionnal Information
Tenalisib is a potent and selective dual PI3Kδ/γ inhibitor with IC50 values of 24.5 nM and 33.2 nM for PI3Kδ and PI3Kγ, respectively. Its selectivity over α and β isoforms are more than 300-fold and 100-fold, respectively.
Storage Conditions
2 years -80 in solvent
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