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Nanvuranlat (JPH203)

Product Specifications

CAS Number

1037592-40-7

Synonyms

KYT-0353, JPH-203SBECD

Target

Amino acid transporter

Applications

Transmembrane Transporters

Smiles

C1=CC=C (C=C1) C2=NC3=CC (=CC (=C3O2) COC4=C (C=C (C=C4Cl) CC (C (=O) O) N) Cl) N

Molecular Formula

C23H19Cl2N3O4

Additionnal Information

Nanvuranlat (JPH203, KYT-0353, JPH-203SBECD), a selective L-type amino acid transporter 1 inhibitor, shows a dramatic inhibition of leucine uptake (IC50=0.06 μM) and cell growth (IC50=4.1 μM) in human colon cancer cells (HT-29), human oral cancer cells (YD-38) and leukemic cells.

Storage Conditions

2 years -80 in solvent

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