Kira6
Product Specifications
CAS Number
1589527-65-0
Target
IRE1
Applications
ER stress & UPR
Smiles
CC (C) (C) C1=NC (=C2N1C=CN=C2N) C3=CC=C (C4=CC=CC=C43) NC (=O) NC5=CC=CC (=C5) C (F) (F) F
Molecular Formula
C28H25F3N6O
Additionnal Information
Kira6 is a potent type II IRE1α kinase inhibitor with an IC50 of 0.6 μM. It dose-dependently inhibits IRE1α (WT) kinase activity, XBP1 RNA cleavage, Ins2 RNA cleavage and oligomerization.
Storage Conditions
2 years -80 in solvent
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