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BTSA1

Product Specifications

CAS Number

314761-14-3

Target

Bcl-2

Applications

Apoptosis

Smiles

C1=CC=C (C=C1) C2=CSC (=N2) N3C (=O) C (=C (N3) C4=CC=CC=C4) N=NC5=NC=CS5

Molecular Formula

C21H14N6OS2

Additionnal Information

BTSA1 is a pharmacologically optimized BAX activator that binds with high affinity and specificity to the N-terminal activation site and induces conformational changes to BAX leading to BAX-mediated apoptosis. It effectively promotes apoptosis in leukemia cell lines and patient samples while sparing healthy cells.

Storage Conditions

2 years -80 in solvent

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