AZD5991
Product Specifications
CAS Number
2143010-83-5
Target
Bcl-2
Applications
Apoptosis
Smiles
CC1=C2C (=NN1C) CSCC3=NN (C (=C3) CSC4=CC5=CC=CC=C5C (=C4) OCCCC6=C (N (C7=C6C=CC (=C27) Cl) C) C (=O) O) C
Molecular Formula
C35H34ClN5O3S2
Additionnal Information
AZD5991 is a macrocyclic MCL-1 inhibitor with sub-nanomolar affinity for MCL-1 (Ki = 0.13 nM) . The binding affinity of AZD5991 is about 25-fold lower for mouse Mcl-1 vs. human Mcl-1 but only four-fold lower for rat Mcl-1.
Storage Conditions
3 years -20°C powder
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6268610-01 0.1 mL
CD8 (CD 8, CD8 Antigen alpha Polypeptide, Leu2 T Lymphocyte Antigen, MAL, OKT8 T Cell Antigen, p32, T Cell Antigen Leu2, T Cell Surface Glycoprotein CD8 alpha Chain) (APC)
Sign In for Pricing
View Details MBS6268610-02 5x 0.1 mL
CD8 (CD 8, CD8 Antigen alpha Polypeptide, Leu2 T Lymphocyte Antigen, MAL, OKT8 T Cell Antigen, p32, T Cell Antigen Leu2, T Cell Surface Glycoprotein CD8 alpha Chain) (APC)
Sign In for Pricing
View Details GTR10428847 96 Well
Canine Calpain small subunit 2 (CAPNS2) ELISA kit
Sign In for Pricing
View Details