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Reparixin (Repertaxin)

Product Specifications

CAS Number

266359-83-5

Synonyms

DF 1681Y

Target

CXCR

Applications

GPCR & G Protein

Smiles

CC (C) CC1=CC=C (C=C1) C (C) C (=O) NS (=O) (=O) C

Molecular Formula

C14H21NO3S

Additionnal Information

Reparixin (Repertaxin, DF 1681Y) is a potent and specific inhibitor of CXCR1 with IC50 of 1 nM. Reparixin (Repertaxin) inhibits PMN migration induced by CXCL8 (IC50 = 1 nM) and rodent PMN chemotaxis induced by CXCL1 and CXCL2. Repertaxin inhibits the response of human PMN to CXCL1, which interacts with CXCR2 (IC50 = 400 nM) .

Storage Conditions

2 years -80 in solvent

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