Reparixin (Repertaxin)
Product Specifications
CAS Number
266359-83-5
Synonyms
DF 1681Y
Target
CXCR
Applications
GPCR & G Protein
Smiles
CC (C) CC1=CC=C (C=C1) C (C) C (=O) NS (=O) (=O) C
Molecular Formula
C14H21NO3S
Additionnal Information
Reparixin (Repertaxin, DF 1681Y) is a potent and specific inhibitor of CXCR1 with IC50 of 1 nM. Reparixin (Repertaxin) inhibits PMN migration induced by CXCL8 (IC50 = 1 nM) and rodent PMN chemotaxis induced by CXCL1 and CXCL2. Repertaxin inhibits the response of human PMN to CXCL1, which interacts with CXCR2 (IC50 = 400 nM) .
Storage Conditions
2 years -80 in solvent
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