What is the catalog number for BML-277 (Chk2 Inhibitor II)?

The catalog number for BML-277 (Chk2 Inhibitor II) is C13550-10mM/1mL.

What sizes are available for BML-277 (Chk2 Inhibitor II)?

BML-277 (Chk2 Inhibitor II) is available in the following size(s): 10 mM/1mL.

Is BML-277 (Chk2 Inhibitor II) in stock?

BML-277 (Chk2 Inhibitor II) is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for BML-277 (Chk2 Inhibitor II)?

BML-277 (Chk2 Inhibitor II) is requires dry ice shipping.

BML-277 (Chk2 Inhibitor II)

Product Specifications

CAS Number

516480-79-8

Target

Chk

Applications

Cell Cycle

Smiles

C1=CC (=CC=C1C2=NC3=C (N2) C=C (C=C3) C (=O) N) OC4=CC=C (C=C4) Cl

Molecular Formula

C20H14ClN3O2

Additionnal Information

BML-277 (Chk2 Inhibitor II) is an ATP-competitive inhibitor of Chk2 with IC50 of 15 nM. It is 1000-fold more selective toward Chk2 serine/threonine kinase than for Chk1 and Cdk1/B kinases. Chk2 Inhibitor II (BML-277) dose dependently protects human CD4 (+) and CD8 (+) T-cells from apoptosis due to ionizing radiation.