Linrodostat (BMS-986205)
Product Specifications
CAS Number
1923833-60-6
Synonyms
ONO-7701
Target
IDO/TDO
Applications
Metabolism
Smiles
CC (C1CCC (CC1) C2=C3C=C (C=CC3=NC=C2) F) C (=O) NC4=CC=C (C=C4) Cl
Molecular Formula
C24H24ClFN2O
Additionnal Information
Linrodostat (BMS-986205, ONO-7701) is an irreversible inhibitor of IDO1 with an IC50 of 1.7 nM. It inhibits kynurenine production with IC50 values of 1.7, 1.1 and > 2000 in human HeLa, HEK293 expressing human IDO-1 and tryptophan-2, 3-dioxygenase cell-based assays.
Storage Conditions
3 years -20°C powder
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