6-Diazo-5-oxo-L-norleucine
Product Specifications
CAS Number
157-03-9
Synonyms
Diazooxonorleucine, 6-Diazo-5-oxo-L-nor-Leucine, L-6-Diazo-5-oxonorleucine, DON
Target
Glutaminase
Applications
Proteases
Smiles
C (CC (=O) C=[N+]=[N-]) C (C (=O) O) N
Molecular Formula
C6H9N3O3
Additionnal Information
6-Diazo-5-oxo-L-norleucine (Diazooxonorleucine, L-6-Diazo-5-oxonorleucine, DON), an antibiotic isolated from Streptomyces, is a glutaminase antagonist with IC50 of ~1 mM for cKGA (kidney-type glutaminase) . 6-Diazo-5-oxo-L-norleucine exhibits analgesic, antibacterial, antiviral and anticancer properties.
Storage Conditions
3 years -20°C powder
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