Derazantinib
Product Specifications
CAS Number
1234356-69-4
Synonyms
ARQ-087
Target
FGFR
Applications
Protein Tyrosine Kinase
Smiles
COCCNCCC1=CC (=CC=C1) NC2=NC=C3CC (C4=CC=CC=C4C3=N2) C5=CC=CC=C5F
Molecular Formula
C29H29FN4O
Additionnal Information
Derazantinib is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with IC50 values of 1.8 nM for FGFR2, and 4.5 nM for FGFR1 and 3, showing lower potency for FGFR4 (IC50=34 nM) . It also inhibits RET, DDR2, PDGFRβ, VEGFR and KIT.
Storage Conditions
3 years -20°C powder
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC402940-100 1x 100 µL
CD79b (B-Cell Marker) (IGB/2940R), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
KN209832BN 1 Kit
Aryl hydrocarbon Receptor (AHR) Human Gene Knockout Kit (CRISPR)
Sign In for Pricing
View Details 
