C188-9
Product Specifications
CAS Number
432001-19-9
Synonyms
TTI 101
Target
STAT
Applications
Apoptosis
Smiles
COC1=CC=C (C=C1) S (=O) (=O) NC2=CC (=C (C3=CC=CC=C32) O) C4=C (C=CC5=CC=CC=C54) O
Molecular Formula
C27H21NO5S
Additionnal Information
C188-9 (TTI 101) is a potent inhibitor of STAT3 that binds to STAT3 with high affinity (KD=4.7±0.4 nM) . C188-9 is well tolerated in mice, shows good oral bioavailability, and is concentrated in tumors.
Storage Conditions
2 years -80 in solvent
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