PRN1371
Product Specifications
CAS Number
1802929-43-6
Target
FGFR
Applications
Protein Tyrosine Kinase
Smiles
CNC1=NC=C2C=C (C (=O) N (C2=N1) CCCN3CCN (CC3) C (=O) C=C) C4=C (C (=CC (=C4Cl) OC) OC) Cl
Molecular Formula
C26H30Cl2N6O4
Additionnal Information
PRN1371 is an irreversible covalent FGFR1-4 kinase inhibitor, with IC50s of 0.6, 1.3, 4.1, 19.3 and 8.1 nM for FGFR1, 2, 3, 4 and CSF1R, respectively.
Storage Conditions
2 years -80 in solvent
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