CEP-40783 (RXDX-106)
Product Specifications
CAS Number
1437321-24-8
Target
Axl
Applications
Protein Tyrosine Kinase
Smiles
CC (C) N1C=C (C (=O) N (C1=O) C2=CC=C (C=C2) F) C (=O) NC3=CC (=C (C=C3) OC4=C5C=C (C (=CC5=NC=C4) OC) OC) F
Molecular Formula
C31H26F2N4O6
Additionnal Information
CEP-40783 (RXDX-106) is an orally-available, potent and selective TAM (TYRO3, AXL, MER) /Met (c-Met) inhibitor displaying low nanomolar biochemical activity and slow (T1/2 >120 min) inhibitor off-rate in peptide phosphorylation assays and in vitro kinase binding assays, respectively.
Storage Conditions
2 years -80 in solvent
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