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Tucidinostat (Chidamide)

Product Specifications

CAS Number

1616493-44-7

Synonyms

HBI-8000, CS-055

Target

HDAC

Applications

DNA Damage/DNA Repair

Smiles

C1=CC (=CN=C1) C=CC (=O) NCC2=CC=C (C=C2) C (=O) NC3=C (C=C (C=C3) F) N

Molecular Formula

C22H19FN4O2

Additionnal Information

Tucidinostat (Chidamide, HBI-8000, CS-055) is a low nanomolar inhibitor of HDAC1, 2, 3, and 10, the HDAC isotypes well documented to be associated with the malignant phenotype with IC50 values of 95, 160, 67, 78 nM for HDAC1, 2, 3, 10 respectively.

Storage Conditions

2 years -80 in solvent

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