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Asciminib (ABL001)

Product Specifications

CAS Number

1492952-76-7

Target

Bcr-Abl

Applications

Protein Tyrosine Kinase

Smiles

C1CN (CC1O) C2=C (C=C (C=N2) C (=O) NC3=CC=C (C=C3) OC (F) (F) Cl) C4=CC=NN4

Molecular Formula

C20H18ClF2N5O3

Additionnal Information

Asciminib (ABL001) is a potent and selective allosteric ABL1 inhibitor with dissociation constant (Kd) of 0.5-0.8 nM and selectivity to the myristoyl pocket of ABL1.

Storage Conditions

2 years -80 in solvent

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