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Roblitinib (FGF401)

Product Specifications

CAS Number

1708971-55-4

Target

FGFR

Applications

Protein Tyrosine Kinase

Smiles

CN1CCN (C (=O) C1) CC2=C (N=C3C (=C2) CCCN3C (=O) NC4=NC=C (C (=C4) NCCOC) C#N) C=O

Molecular Formula

C25H30N8O4

Additionnal Information

Roblitinib (FGF401) is an FGFR4-selective inhibitor with an IC50 of 1.9 nM. It binds in a reversible covalent manner to the FGFR4 kinase domain and shows at least 1,000 fold selectivity against of panel of 65 kinases in biochemical assays.

Storage Conditions

2 years -80 in solvent

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