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WT161

Product Specifications

CAS Number

1206731-57-8

Target

HDAC

Applications

DNA Damage/DNA Repair

Smiles

C1=CC=C (C=C1) N (C2=CC=CC=C2) C3=CC=C (C=C3) C=NNC (=O) CCCCCCC (=O) NO

Molecular Formula

C27H30N4O3

Additionnal Information

WT161 is a potent, selective, and bioavailable HDAC6 inhibitor with IC50 values of 0.4 nM, 8.35 nM and 15.4 nM for HDAC6, HDAC1 and HDAC2, respectively; shown to have >100-fold selectivity over other HDACs. WT161 induces apoptosis.

Storage Conditions

2 years -80 in solvent

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