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PF-06726304

Product Specifications

CAS Number

1616287-82-1

Synonyms

PF-6726304

Target

Histone Methyltransferase

Applications

Epigenetics

Smiles

CC1=CC (=C (C (=O) N1) CN2CCC3=C (C=C (C (=C3C2=O) Cl) C4=C (ON=C4C) C) Cl) C

Molecular Formula

C22H21Cl2N3O3

Additionnal Information

PF-06726304 is a selective EZH2 inhibitor with Ki values of 0.7 nM and 3 nM for WT EZH2 and Y641N respectively; also inhibits H3K27me3 with the IC50 value of 15 nM.

Storage Conditions

2 years -80 in solvent

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