PF-06726304
Product Specifications
CAS Number
1616287-82-1
Synonyms
PF-6726304
Target
Histone Methyltransferase
Applications
Epigenetics
Smiles
CC1=CC (=C (C (=O) N1) CN2CCC3=C (C=C (C (=C3C2=O) Cl) C4=C (ON=C4C) C) Cl) C
Molecular Formula
C22H21Cl2N3O3
Additionnal Information
PF-06726304 is a selective EZH2 inhibitor with Ki values of 0.7 nM and 3 nM for WT EZH2 and Y641N respectively; also inhibits H3K27me3 with the IC50 value of 15 nM.
Storage Conditions
2 years -80 in solvent
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