What is the catalog number for CBL0137 HCl?

The catalog number for CBL0137 HCl is C13442-25mg.

What sizes are available for CBL0137 HCl?

CBL0137 HCl is available in the following size(s): 25 mg.

Is CBL0137 HCl in stock?

CBL0137 HCl is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for CBL0137 HCl?

CBL0137 HCl is requires dry ice shipping.

CBL0137 HCl

Product Specifications

CAS Number

1197397-89-9

Synonyms

CBLC137 HCl, Curaxin 137 HCl

Target

P53

Applications

Apoptosis

Smiles

CC (C) NCCN1C2=C (C=C (C=C2) C (=O) C) C3=C1C=CC (=C3) C (=O) C.Cl

Molecular Formula

C21H24N2O2.HCl

Additionnal Information

CBL0137 (CBLC137, Curaxin 137) HCl activates p53 and inhibits NF-κB with EC50s of 0.37 μM and 0.47 μM in the cell-based p53 and NF-kB reporter assays, respectively. It also inhibits histone chaperone FACT (facilitates chromatin transcription complex) .