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Citarinostat (ACY-241)

Product Specifications

CAS Number

1316215-12-9

Synonyms

HDAC-IN-2

Target

HDAC

Applications

DNA Damage/DNA Repair

Smiles

C1=CC=C (C=C1) N (C2=CC=CC=C2Cl) C3=NC=C (C=N3) C (=O) NCCCCCCC (=O) NO

Molecular Formula

C24H26ClN5O3

Additionnal Information

Citarinostat (ACY-241, HDAC-IN-2) is an orally available selective HDAC6 inhibitor with IC50 of 2.6 nM and 46 nM for HDAC6 and HDAC3, respectively. It has 13 to 18-fold selectivity towards HDAC6 in comparison to HDAC1-3.

Storage Conditions

2 years -80 in solvent

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