VH298
Product Specifications
CAS Number
2097381-85-4
Target
E3 Ligase
Applications
Ubiquitin
Smiles
CC1=C (SC=N1) C2=CC=C (C=C2) CNC (=O) C3CC (CN3C (=O) C (C (C) (C) C) NC (=O) C4 (CC4) C#N) O
Molecular Formula
C27H33N5O4S
Additionnal Information
VH298 is a potent VHL (Von Hippel-Lindau, the E3 ligase) inhibitor that stabilizes HIF-α. VH298 blocks the VHL:HIF-α interaction with Kd of 90 nM in isothermal titration calorimetry (ITC) and 80 nM in a competitive fluorescence polarization assay. VH-298 can be used in PROTAC technology.
Storage Conditions
3 years -20°C powder
More Discoveries
Explore Other Products
Browse additional items from our catalog
35314121 3x 1.0µg DNA
OR52A1 CRISPRa sgRNA lentivector (set of three targets)(Human)
Sign In for Pricing
View Details 
MBS9355007-01 48 Well
Canine BRICHOS Domain-Containing Protein C16orf79 (C16ORF79) ELISA Kit
Sign In for Pricing
View Details 
MBS9355007-02 96 Well
Canine BRICHOS Domain-Containing Protein C16orf79 (C16ORF79) ELISA Kit
Sign In for Pricing
View Details MBS9355007-03 5x 96 Well
Canine BRICHOS Domain-Containing Protein C16orf79 (C16ORF79) ELISA Kit
Sign In for Pricing
View Details MBS9355007-04 10x 96 Well
Canine BRICHOS Domain-Containing Protein C16orf79 (C16ORF79) ELISA Kit
Sign In for Pricing
View Details GTR15272596 1 Vial
Lentiviral mouse Ppp1r3f shRNA (UAS) - Lentiviral mouse Ppp1r3f shRNA (UAS, iRFP) plasmid
Sign In for Pricing
View Details