VH298
Product Specifications
CAS Number
2097381-85-4
Target
E3 Ligase
Applications
Ubiquitin
Smiles
CC1=C (SC=N1) C2=CC=C (C=C2) CNC (=O) C3CC (CN3C (=O) C (C (C) (C) C) NC (=O) C4 (CC4) C#N) O
Molecular Formula
C27H33N5O4S
Additionnal Information
VH298 is a potent VHL (Von Hippel-Lindau, the E3 ligase) inhibitor that stabilizes HIF-α. VH298 blocks the VHL:HIF-α interaction with Kd of 90 nM in isothermal titration calorimetry (ITC) and 80 nM in a competitive fluorescence polarization assay. VH-298 can be used in PROTAC technology.
Storage Conditions
3 years -20°C powder
More Discoveries
Explore Other Products
Browse additional items from our catalog
RC219035L3 10 µg
Clathrin light chain (CLTA) (NM_007096) Human Tagged Lenti ORF Clone
Sign In for Pricing
View Details 
ELI-12775m 96 Tests
Mouse PR domain zinc finger protein 5, Prdm5 ELISA KIT
Sign In for Pricing
View Details 589906 96 Tests
Vestigial Like Protein 1 (VGLL1) BioAssayTM ELISA Kit (Human)
Sign In for Pricing
View Details