CAY10585 (LW 6)
Product Specifications
CAS Number
934593-90-5
Synonyms
AC1-001
Target
HIF
Applications
Angiogenesis
Smiles
COC (=O) C1=CC (=C (C=C1) O) NC (=O) COC2=CC=C (C=C2) C34CC5CC (C3) CC (C5) C4
Molecular Formula
C26H29NO5
Additionnal Information
CAY10585 (LW 6) is a hypoxia-inducible factor 1 (HIF) inhibitor which potently inhibits HIF-1α accumulation by degrading HIF-1α without affecting the HIF-1a mRNA levels during hypoxia. LW6 inhibits HIF and MDH2 expression with IC50 values of 4.4 and 6.3 μM, respectively.
Storage Conditions
2 years -80 in solvent
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