Fenebrutinib (GDC-0853)
Product Specifications
CAS Number
1434048-34-6
Target
BTK
Applications
Protein Tyrosine Kinase
Smiles
CC1CN (CCN1C2=CN=C (C=C2) NC3=CC (=CN (C3=O) C) C4=C (C (=NC=C4) N5CCN6C7=C (CC (C7) (C) C) C=C6C5=O) CO) C8COC8
Molecular Formula
C37H44N8O4
Additionnal Information
Fenebrutinib (GDC-0853) is a potent, selective, and non-covalent bruton's tyrosine kinase (BTK) inhibitor with an Ki value of 0.91 nM for Btk with >100-fold selectivity over 3 off-targets (Bmx :153-fold, Fgr: 168-fold, Src:131-fold) .
Storage Conditions
3 years -20°C powder
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