What is the catalog number for Stenoparib (E7449)?

The catalog number for Stenoparib (E7449) is C13406-1g.

What sizes are available for Stenoparib (E7449)?

Stenoparib (E7449) is available in the following size(s): 1 g.

Is Stenoparib (E7449) in stock?

Stenoparib (E7449) is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for Stenoparib (E7449)?

Stenoparib (E7449) is requires dry ice shipping.

Stenoparib (E7449)

Product Specifications

CAS Number

1140964-99-3

Synonyms

2X-121, MGI25036

Target

PARP

Applications

DNA Damage/DNA Repair

Smiles

C1C2=CC=CC=C2CN1CC3=NC4=NNC (=O) C5=C4C (=CC=C5) N3

Molecular Formula

C18H15N5O

Additionnal Information

Stenoparib (E7449, 2X-121, MGI25036) is an orally bioavailable, brain penetrable, small molecule dual inhibitor of PARP1/2 and also inhibits PARP5a/5b, otherwise known as tankyrase1 and 2 (TNKS1/2), important regulators of canonical Wnt/β-catenin signaling. It has IC50 values of 1.0 and 1.2 nM for PARP1 and 2, respectively.