PACAP 6-38 acetate

CSCCC (NC (=O) C (CCC (N) =O) NC (=O) C (CCCCN) NC (=O) C (CCCNC (N) =N) NC (=O) C (CC1=CC=C (O) C=C1) NC (=O) C (CCCNC (N) =N) NC (=O) C (CO) NC (=O) C (CC2=CC=C (O) C=C2) NC (=O) C (CO) NC (=O) C (CC (O) =O) NC (=O) C (NC (=O) C (N) CC3=CC=CC=C3) C (C) O) C (=O) NC (C) C (=O) NC (C (C) C) C (=O) NC (CCCCN) C (=O) NC (CCCCN) C (=O) NC (CC4=CC=C (O) C=C4) C (=O) NC (CC (C) C) C (=O) NC (C) C (=O) NC (C) C (=O) NC (C (C) C) C (=O) NC (CC (C) C) C (=O) NCC (=O) NC (CCCCN) C (=O) NC (CCCNC (N) =N) C (=O) NC (CC5=CC=C (O) C=C5) C (=O) NC (CCCCN) C (=O) NC (CCC (N) =O) C (=O) NC (CCCNC (N) =N) C (=O) NC (C (C) C) C (=O) NC (CCCCN) C (=O) NC (CC (N) =O) C (=O) NC (CCCCN) C (N) =O

PACAP 6-38 acetate is a PACAP (pituitary adenylate cyclase-activating polypeptide) non-stimulating competitive antagonist with an IC50 value of 2 nM. It also acts as a functional CARTp antagonist in vivo.