RRx-001
Product Specifications
CAS Number
925206-65-1
Target
Dehydrogenase
Applications
Metabolism
Smiles
C1C (CN1C (=O) CBr) ([N+] (=O) [O-]) [N+] (=O) [O-]
Molecular Formula
C5H6BrN3O5
Additionnal Information
RRx-001 is a novel epigenetic modulator with potential radiosensitizing activity. It inhibits glucose 6-phosphate dehydrogenase (G6PD) in human tumor cells, binds hemoglobin and drives RBC-mediated redox reactions under hypoxia. RRx-001 triggers apoptosis and exhibits anticancer activity.RRx-001 is also a downregulator of the CD47- SIRPα checkpoint pathway.
Storage Conditions
2 years -80 in solvent
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