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KRIBB11

Product Specifications

CAS Number

342639-96-7

Target

HSP (HSP90)

Applications

Cytoskeletal Signaling

Smiles

CNC1=NC (=C (C=C1) [N+] (=O) [O-]) NC2=CC3=C (C=C2) NN=C3

Molecular Formula

C13H12N6O2

Additionnal Information

KRIBB11 abolishes the heat shock-induced luciferase activity with an IC50 of 1.2 μM. It is an inhibitor of the transcription factor Heat Shock Factor 1 (HSF1) . KRIBB11 induces growth arrest and apoptosis.

Storage Conditions

2 years -80 in solvent

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