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INDY

Product Specifications

CAS Number

1169755-45-6

Target

DYRK

Applications

Protein Tyrosine Kinase

Molecular Formula

C12H13NO2S

Additionnal Information

INDY, a benzothiazole derivative is a potent and ATP-competitive inhibitor of Dyrk1A and Dyrk1B with an IC50 value of 0.24 μM and Ki value of 0.18 μM, respectively. INDY diminishes the self-renewal capacity of normal and tumorigenic cells in primary Glioblastoma (GBM) cell lines and neural progenitor cells.
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