INDY
Product Specifications
CAS Number
1169755-45-6
Target
DYRK
Applications
Protein Tyrosine Kinase
Molecular Formula
C12H13NO2S
Additionnal Information
INDY, a benzothiazole derivative is a potent and ATP-competitive inhibitor of Dyrk1A and Dyrk1B with an IC50 value of 0.24 μM and Ki value of 0.18 μM, respectively. INDY diminishes the self-renewal capacity of normal and tumorigenic cells in primary Glioblastoma (GBM) cell lines and neural progenitor cells.
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