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S63845

Product Specifications

CAS Number

1799633-27-4

Target

Bcl-2

Applications

Apoptosis

Smiles

CC1=C (C=CC (=C1Cl) OCCN2CCN (CC2) C) C3=C (SC4=NC=NC (=C34) OC (CC5=CC=CC=C5OCC6=CC=NN6CC (F) (F) F) C (=O) O) C7=CC=C (O7) F

Molecular Formula

C39H37ClF4N6O6S

Additionnal Information

S63845 is a new, selective MCL-1 inhibitor with the Kd value of 0.19 nM and has no discernible binding to the other BCL-2 members, BCL-2 or BCL-XL.

Storage Conditions

2 years -80 in solvent

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