WNK463
Product Specifications
CAS Number
2012607-27-9
Target
Serine/threonin kinase
Applications
Cell Cycle
Smiles
CC (C) (C) NC (=O) C1=CN=CN1C2CCN (CC2) C3=NC=C (C=C3) C4=NN=C (O4) C (F) (F) F
Molecular Formula
C21H24F3N7O2
Additionnal Information
WNK463 is a pan-WNK-kinase inhibitor. It potently inhibits the in vitro kinase activity of all four WNK family members (WNK1, WNK2, WNK3, and WNK4) with IC50 of 5nM, 1nM, 6nM, and 9nM.
Storage Conditions
2 years -80 in solvent
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USP9Y (Probable Ubiquitin Carboxyl-terminal Hydrolase FAF-Y, Deubiquitinating Enzyme FAF-Y, Fat Facets Protein-related, Y-linked, Ubiquitin Thioesterase FAF-Y, Ubiquitin-specific Protease 9, Y Chromosome, Ubiquitin-specific-processing Protease FAF-Y, DFFR
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