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APS-2-79 HCl

Product Specifications

CAS Number

2002381-31-7

Target

MEK

Applications

Protein Tyrosine Kinase

Smiles

CC1=C (C=CC (=C1) OC2=CC=CC=C2) NC3=NC=NC4=CC (=C (C=C43) OC) OC.Cl

Molecular Formula

C23H21N3O3.HCl

Additionnal Information

APS-2-79 is a MAPK antagonist that modulating KSR-dependent MAPK signalling by antagonizing RAF heterodimerization as well as the conformational changes required for phosphorylation and activation of KSR-bound MEK. IC50=120 ± 23 nM.

Storage Conditions

2 years -80 in solvent

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