CPI-455 HCl
Product Specifications
CAS Number
2095432-28-1
Target
Histone Demethylase
Applications
Epigenetics
Smiles
CC (C) C1=C (N=C2C (=CNN2C1=O) C#N) C3=CC=CC=C3.Cl
Molecular Formula
C16H15ClN4O
Additionnal Information
CPI-455 HCl is a specific KDM5 inhibitor with a half-maximal inhibitory concentration (IC50) of 10 ± 1 nM for full-length KDM5A in enzymatic assays, elevating global levels of H3K4 trimethylation (H3K4me3) and decreased the number of DTPs in multiple cancer cell line models treated with standard chemotherapy or targeted agents.
Storage Conditions
2 years -80 in solvent
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