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PF-3644022

Product Specifications

CAS Number

1276121-88-0

Target

MAPKAPK2

Applications

MAPK

Smiles

CC1CNC2=C (SC3=C2C4=C (C=C3) N=C (C=C4) C5=CN=C (C) C=C5) C (=O) N1

Molecular Formula

C21H18N4OS

Additionnal Information

PF-3644022 is a potent freely reversible ATP-competitive inhibitor of MAPKAPK2 (MK2) with an Ki of 3 nM. PF-3644022 also potently inhibits TNFα production with an IC50 of 160 nM.

Storage Conditions

3 years -20°C powder

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