PF-3644022
Product Specifications
CAS Number
1276121-88-0
Target
MAPKAPK2
Applications
MAPK
Smiles
CC1CNC2=C (SC3=C2C4=C (C=C3) N=C (C=C4) C5=CN=C (C) C=C5) C (=O) N1
Molecular Formula
C21H18N4OS
Additionnal Information
PF-3644022 is a potent freely reversible ATP-competitive inhibitor of MAPKAPK2 (MK2) with an Ki of 3 nM. PF-3644022 also potently inhibits TNFα production with an IC50 of 160 nM.
Storage Conditions
3 years -20°C powder
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