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Bitopertin

Product Specifications

CAS Number

845614-11-1

Synonyms

RG1678, RO-4917838

Target

GlyT

Applications

Neuronal Signaling

Smiles

CC (C (F) (F) F) OC1=C (C=C (C=C1) S (=O) (=O) C) C (=O) N2CCN (CC2) C3=C (C=C (C=N3) C (F) (F) F) F

Molecular Formula

C21H20F7N3O4S

Additionnal Information

Bitopertin (RG1678, RO-4917838) is a potent inhibitor of glycine transporter 1 (GlyT1), with Ki of 8.1 nM for human hGlyT1b and IC50 of 22-25 nM in Chinese hamster ovary cells.

Storage Conditions

2 years -80 in solvent

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